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Iron (Fe) sensing in plants is an essential, finely-tuned process that is under intense investigation. Nguyen et al., (on pp. 829-841) found that altering Fe levels in or around the vasculature changes the timing and magnitude of Fe deficiency responses in a leaf-specific manner. These results suggest that individual leaves have autonomous mechanisms to sense Fe levels.
The cover image shows an Arabidopsis leaf expressing a fluorescent protein (GFP) expressed under the control of a cell specific promoter (SUC2p) in the companion cells only, which are responsible for loading the phloem for long-distance transport of nutrients and signaling molecules. Image supplied by Dr. Samuel McInturf (Division of Plant Sciences and Technology, C.S. Bond Life Sciences Center, University of Missouri, Columbia, USA).
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